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Unspecified Hepatitis


Cause: Hepatitis D virus and hepatitis E virus. Hepatitis D virus infection always occurs with hepatitis B infection, either with a chronic hepatitis B infection (superinfection) or as two simultaneous new infections (coinfection).

Illness and treatment: Hepatitis D and E typically have abrupt onset of fever, nausea, and abdominal pain followed by jaundice. Hepatitis D may progress to chronic hepatitis.

Sources: Humans are the reservoir for hepatitis D, which is usually transmitted by contact with blood or body fluids, particularly sharing drug paraphernalia. Humans and animals (swine) are the reservoir for hepatitis E which is transmitted most commonly through fecally contaminated food, water, and environment.

Additional risks: Pregnant women have higher risk for hepatitis E complications. Japan has reported more virulent hepatitis E strains.

Prevention: To avoid simultaneous hepatitis B infection, immunize all children and any adults with risks for exposure. Use safe sexual practices, avoid sharing drug paraphernalia, and screen blood and tissue products to prevent hepatitis D transmission. Use precautions while traveling to ensure safe food and water to avoid hepatitis E infection.

Recent Washington trends: Reports are rare. Cases of hepatitis D are typically associated with injection drug use. Cases of hepatitis E are typically travel associated.

2008: Three cases of hepatitis D were reported.

Purpose of Reporting and Surveillance

  • To better characterize the epidemiology of infectious hepatitis not due to hepatitis A, B, or C viruses.
  • To recommend appropriate preventive measures, including immunization against other types of hepatitis which are vaccine-preventable.

Legal Reporting Requirements

  • Health care providers: notifiable to local health jurisdiction within 3 work days

  • Hospitals: notifiable to local health jurisdiction within 3 work days

  • Laboratories: no requirements for reporting

  • Local health jurisdictions: notifiable to Washington State Department of Health (DOH) Communicable Disease Epidemiology Section (CDES) within 7 days of case investigation completion or summary information required within 21 days

Last update
November 2009

Unspecified Hepatitis Resources

General Information

Hepatitis D
Fact Sheet

(Web format)

Reporting Forms

Unspecified Hepatitis Reporting Form
(PDF Format)

Public Health and Health Care

Surveillance and Reporting Guidelines
(PDF format)
CDC Guidelines for Surveillance and Case Management

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Communicable Disease Epidemiology
Office of Epidemiology
Washington State Department of Health
MS: K17-9, 1610 NE 150th St.
Shoreline, WA 98155-9701

Consultation and technical assistance are available to local health jurisdictions in Washington State:
Phone (206) 418-5500

FAX (206) 418-5515

24-hour contact (inside Washington State only)  1-877-539-4344

Washington residents can contact their local health jurisdictions for assistance


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