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Cryptococcal Disease
(Rare Disease of Public Health Significance)


Cause: Fungus Cryptococcus. Notifiable condition surveillance is only for C. gattii.

Illness and treatment: Symptoms include severe cough with shortness of breath, chills, night sweats, and loss of appetite. Typical presentations are meningitis and pneumonia. Infection of the kidneys, prostate, and bone may also occur. Treatment is with antifungals.

Sources: C. gattii is an environmental fungus that has been isolated from native trees, soil, air, and water in the Pacific Northwest. Exposure is through inhalation of the organism.

Prevention: There are no specific precautions. Consult a health care provider for any severe or persistent respiratory symptoms.

Recent Washington trends: In 2005, 3 cats living near the Canadian border were diagnosed with C. gattii. In 2006, C. gatti was found in soil from Whatcom County. Also that year, 2 state residents with cryptococcal disease were identified who may have been locally exposed.

2008: One human case was reported from Whatcom County. The case had traveled to Vancouver, BC during the exposure period.

Purpose of Reporting and Surveillance

  • To detect the emergence of Cryptococcus gattii in Washington
  • To improve the number of suspected cases that are laboratory confirmed
  • To monitor trends in the epidemiology of Cryptococcal disease

Legal Reporting Requirements

Human or animal infections with C. gattii  are reportable in Washington State as rare diseases of public health significance.

  • Healthcare providers: immediately notifiable to Local Health Jurisdiction

  • Hospitals: immediately notifiable to Local Health Jurisdiction

  • Laboratories:  no requirements for reporting

  • Local health jurisdictions:  immediately notifiable to DOH Communicable Disease Epidemiology: 1-877-539-4344

Last update
November 2009

Cryptococcal Disease Resources

General Information

Fact Sheet
(Web format)
(PDF format)

Reporting Forms

Cryptococcal Disease Reporting Form
(PDF Format)

Public Health and Health Care

Additional Resources
(PDF format)

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Communicable Disease Epidemiology
Office of Epidemiology
Washington State Department of Health
MS: K17-9, 1610 NE 150th St.
Shoreline, WA 98155-9701

Consultation and technical assistance are available to local health jurisdictions in Washington State:
Phone (206) 418-5500

FAX (206) 418-5515

24-hour contact (inside Washington State only)  1-877-539-4344

Washington residents can contact their local health jurisdictions for assistance


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